This is my system. I have 2 JL 10w3v2 subs powered off a JL 500/1 amp. Focal Polyglass 6.5"s produce the midbass and Focal Polyglass 4"s handle the mids while 1" Focal tweeters blast the highs. All the components are powered by a JL 300/4 amp. The Panasonic CQ-DFX983U HU spits out the tunes with style. Build up pics are on page 3. 
The vinyl covered boxes are made from fiberglass and MDF. The amp rack is made from MDF and plexiglass which I hope to illuminate with some sort of light. I'm working on some fiberglass doorpanels to accommodate the Focal 6.5"s because they are too deep for the stock location.
As promised, here are some pics of the door panels. They are not finished. They still have to be covered in vinyl... they are primered black right now.
Future plans include multimedia, possibly a integrated PC, a blowthrough with fiberglass face plate and a welded in shell in the bed. I'm also going to replace the 4" speakers with either 6.5"s or 5 1/4" Focals.